It is time to stop treating the Thyroid as the only organ in the body. While the focus is primarily on TSH, T4, T3, fT4, Ft3, rT3, TPO & TAA Antibodies. There are other factors that can cause “Low Thyroid” symptoms. Thyroid advocates and support groups treat the thyroid like it is the only organ in the body. In Chapter Four of Dr. Kharrazian’s best selling thyroid book “Why Do I Still Have Thyroid Symptoms? When My Lab Tests are Normal“, six different patterns of low thyroid function, only one of which is treatable with thyroid replacement medication or iodine/selenium supplementation. This is because most people with “symptoms” of low thyroid have functional hypothyroidism due to other dysfunctional organ(s) or microbial infestation and not an actual “thyroid” disease.
Some other aspect of their health is breaking down and producing “low thyroid symptoms”. For instance, insulin resistance associated with “Thyroid Overconversion” produced symptoms of fatigue, weight gain, thinning of hair and scalp. You are allowed to have more than one organ dysfunctioning at the same time. It is called Multiple Organ Dysfunction Syndrome.
While writing this post, a review of Thyroid / Hashimoto social media sites including Dr. Wentz and Mary Shamon revealed no mention of the five none-thyroid patterns in Dr. Kharrazian’s book. Not only were the five none-thyroid patterns never mentioned. All health conditions were attributed back to the thyroid. It was if they needed to fix the problem with a nail but lacked the proper tools.
While the focus is primarily on TSH, T4, T3, fT4, Ft3, rT3, TPO & TAA Antibodies. There are other factors that can cause “Low Thyroid” symptoms.
The focus is typically on on thyroid markers on Social Media groups and the Medical Community. It is as if the only organ in the body is the thyroid. The primary focus is on “Low Thyroid”, while Hashimoto’s is the most common cause of hypothyroidism. The fact that there are six other factors that cause “Low Thyroid Function”. Only one of which successfully supports, it at all, with thyroid replacement hormone medication or iodine supplementation.
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This is because most people with symptoms of hypothyroidism have “functional hypothyroidism” and not an actual thyroid disease. Some aspect of their health is breaking down and producing hypothyroid symptoms, but the condition does not warrant lifelong medication or iodine supplementation. It’s all a matter of learning how to look at the entire body, knowing there are other factors that cause “Low Thyroid Symptoms”.
T3 and T4 regulation
The production of thyroxine (T4) and triiodothyronine (T3) is regulated by thyroid-stimulating hormone (TSH), released by the anterior pituitary. The thyroid and thyrotropes (cells in the anterior pituitary) form a negative feedback loop: TSH production is suppressed when the T4 levels are high, and vice versa. The TSH production itself is modulated by thyrotropin-releasing hormone (TRH), which is produced by the hypothalamus and secreted at an increased rate in situations such as cold (in which an accelerated metabolism would generate more heat). TSH production is blunted by somatostatin (SRIH), rising levels of glucocorticoids (cortosol) and sex hormones (estrogen and testosterone), and excessively high blood iodide concentration.
There are other factors to consider as well that inhibit the production of thyroid hormones. A short list includes:
- Lectins can attach themselves to Thyroid Stimulating Hormone (TSH) receptor sites and play havoc in two ways. The first is that the Lectins are able to “fit” the receptor sufficiently enough to stimulate the thyroid but the effects are different in those with hyperthyroid or Autoimmune Hyperthyroid and low thyroid or Hashimoto thyroiditis. The second effect is that the immune response to the lectin stimulation starts an autoimmune response to the thyroid stimulating hormone (TSH) receptors on the thyroid.
- The seasonal influences of Melatonin and/or melatonin supplementation. Melatonin has a thyroid function suppressing action. Melatonin has an inhibitory action on the Hypothalamic-pituitary-thyroid (HPT) axis.
- Oral bacteria infection attack on the thyroid. The damage caused to the gland results in the release of a conspicuous quantity of thyroid hormones, thus causing a thyrotoxic pattern: temperature, cutaneous pallor, excessive perspiration, tremor, tiredness, weight loss, increased appetite, and tachycardia.
- The status of your immune system on a daily/seasonal basis, or with exposure to bacteria and lectins.
- Multiple Organ Dysfunction Syndrome
Read More about the Six Patterns of Low Thyroid Function
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- The only time to use Iodine or Selenium to restore normal Thyroid Function.
- Primary Hypothyroidism is a thyroid treatable condition.
- Suppressed Hypothalamus-Pituitary function from exogenous Melatonin, Somatostatin, Impaired Vasomotor control leading to Ischemia of the Blood-Brain-Barrier, Hypothalamus, Hippocampus and Pituitary.
- Hippocampus, hypothalamic and pituitary suppression of Thyroid Stimulating Hormone (TSH) production results in Low Thyroid Symptoms.
- Cortisol imbalances causing downstream production of thyroid suppressing corticosteroid hormones measured by the Genova Complete Hormone Panel.
- Thyroid hormone suppressing corticosteroid hormones mimic Low Thyroid Symptoms.
- Thyroid Overconversion is directly linked to Insulin Resistance and Polycystic Ovarian Syndrome (PCOS).
- Insulin resistance and PCOS symptoms mimic Low Thyroid Symptoms.
- Thyroid Hormone Binding Elevation is a pattern associated with elevation of Multiple Estrogens caused by impaired clearance due to Hepatic Portal Hypertension, and/or bacterial toxins preventing clearance of hormones from the body. Another factor to consider is alteration to the Hypothalamus-Pituitary-Gonad (HPG) Axis.
- Elevation in Estrogen mimic Low Thyroid Symptoms.
- Thyroid Resistance is caused by cellular inflammation occurring throughout the body. An possibility is failure to adequately monitor Thyroid Hormone Medications.
- Cellular Inflammation and improper Thyroid Hormone Medication dosage mimics Low Thyroid Symptoms.