Do you suspect you are suffering from food sensitivities? Does it occur during inopportune moments? Have your tried eliminating foods from your diet only to find more and more foods causing problems for you? Does this make shopping impossible? Do you find yourself obsessed with finding someone on the Internet with similar symptoms to you? What you really need is to be looking in the mirror, at you and your unique immune responses. This is best done by Mediator Release testing.
Over the years of clinical experience has shown over and over that antibodies associated with food sensitivity, such as food-specific IgG or IgA, do not reliably correlate with inflammation or symptoms.
What happen when lab tests come back negative and positive? Lab test are about probabilities not absolutes. A positive antibody test only tells an immune reaction is likely to occur. Few recognize the reaction must be carried out through the cytokines, chemokines and neurotransmitters of the NEI Supersystem while being influenced by hormones.
This is why addressing the NEI Supersystem may be the best first course of action.
Immunoglobulins work like a lock and key. There is a critical component to this theory: Immunoglobulins are designed to work for only one reaction; there is only one key that fits the lock perfectly. This prevents an uncontrolled immune response. In the Lock and Key Analogy, the antigen (gluten in the example) is the “key”. The key must fit perfectly into the active site that is on the immunoglobulin, or the “key hole in the lock (sIgA are the Lock in the example).
Bacteria, parasites and digestive enzymes damage immunoglobulins damaging the keyhole in the lock. When the lock is damaged any key can work to trigger an immune response. As a result of this lab testing can be useful or misleading and confusing. Microbes not only cleave immunoglobulins as part of their survival strategy. They also have the ability to hack into the NEI supersystem altering the immune response. Microbes stimulate the production of immune mediators.
Mediator release is the key event that leads to every negative effect you suffer. Mediators release occurs independent of the presence of antibodies. What matters clinically is the mediator release, and that an inflammatory response has occurred – not that an antibody is elevated.
MRT is one of the sensitivity blood test used that quantifies the degree of the inflammatory mediator response to food. That means in addition to identifying the foods with the highest degree of reaction, more importantly, MRT is able to identify the foods that have the lowest degree of reaction in sensitivity pathways.
Immunologically speaking, the least reactive MRT foods are your patient’s best foods (as long as you have taken account of any food allergies and celiac disease). The least reactive MRT tested foods have the highest probability of being well-tolerated. And if they are foods you like to eat, which they usually are, those are the foods that will form the basis for the multi-phased LEAP eating plan.